This is a simple tool to generate hypothetical point mutations in a sequence. It was written to provide a convenient way to simplify and randomize the process of generating mutants in a laboratory setting. One or more gene sequences are entered in FASTA format and then one or more mutants (point mutations) are randomly generated for each source sequence. You may generate synonymous mutations, non-synonymous mutations or both. The translation table (NCBI) may be selected to fit your particular organism.